α-[[(1,1-Dimethylethoxy)carbonyl]amino]cyclopentaneacetic acid - Names and Identifiers
α-[[(1,1-Dimethylethoxy)carbonyl]amino]cyclopentaneacetic acid - Physico-chemical Properties
Molecular Formula | C12H21NO4
|
Molar Mass | 243.3 |
Storage Condition | Sealed in dry,Room Temperature |
α-[[(1,1-Dimethylethoxy)carbonyl]amino]cyclopentaneacetic acid - Introduction
[nature]]:
-Appearance: White crystalline solid
-Solubility: Can be dissolved in common organic solvents, such as methanol, ethanol and dimethyl sulfoxide
-Molecular Weight: 221.28
-melting point: about 68-70 ℃
[use]]:
Cyclopentaneaceticacid, a-[[(1,1-dimenthylethoxy) carbonyl]amino]-is usually used as a protecting group or intermediate in organic synthesis. It is possible to remove the Boc protecting group by a deprotecting group reaction to obtain DL-cyclopentylglycine. DL-Cyclopentylglycine can be used in the synthesis of polypeptides, drugs and other organic compounds.
[preparation method]]:
Cyclopentaneaceticacid, the preparation of a-[[(1,1-dimenthylethoxy) carbonyl]amino]-is generally carried out by the following steps:
1. DL-cyclopentylglycine is reacted with 1,1-dimethylethyl ester and diethylamine under anhydrous conditions to generate Cyclopentaneaceticacid, a-[[(1,1-dimethyllethoxy) carbonyl]amino]-.
2. After completion of the reaction, the pure product is obtained by crystallization or chromatography purification.
[Safety Information]]:
- Cyclopentaneaceticacid, a-[[(1,1-dimenthylethoxy) carbonyl]amino]-generally has low toxicity under normal use conditions.
-However, as a chemical substance, you must pay attention to personal protective measures, such as wearing appropriate protective gloves and glasses, and avoiding inhalation or contact with skin.
-During operation, well-ventilated laboratory conditions should be used and safe operating procedures should be followed.
-For the disposal of this compound, it should be handled in accordance with local regulations.
Last Update:2024-04-09 20:13:35